The following is a list of Illinois High School Association member conferences. Schools that belong to these conferences compete with each other on a local level in athletics and non-athletic activities. As of the 2023-24 school year, there are 70 conferences within the IHSA.
Current Conferences
- Apollo Conference
 - Big Northern Conference
 - Big Twelve Conference
 - Black Diamond Conference
 - Cahokia Conference (contains three divisions)
 - Central Illinois Conference
 - Central State Eight Conference
 - Central Suburban League (contains two divisions)
 - Chicago Catholic League (contains two divisions)
 - Chicago Prep Conference
 - Chicago Public High School League (contains ten divisions)
 - Chicagoland Christian Conference
 - DuKane Conference
 - DuPage Valley Conference
 - East Central Illinois Conference
 - East Suburban Catholic Conference
 - Egyptian Illini Conference
 - Fox Valley Conference
 - Gateway Metro Conference
 - Girls Catholic Athletic Conference
 - Greater Egyptian Conference
 - Heart of Illinois Conference
 - Illini Prairie Conference
 - Illinois Central Eight Conference
 - Independent School League
 - Inter County Athletic Conference
 - Interstate Eight Conference
 - Kishwaukee River Conference
 - Lake Shore Athletic Conference
 - Lincoln Prairie Conference
 - Lincoln Trail Conference
 - Little Illini Conference
 - Little Okaw Valley Conference
 - Little Ten Conference
 - Metro Suburban Conference
 - Metropolitan Prep Conference
 - Mid-Illini Conference
 - Midland Trail Conference
 - Mid-Suburban League (contains two divisions)
 - Mississippi Valley Conference
 - MSM Conference
 - National Trail Conference
 - Noble Athletic Conference
 - North Suburban Conference
 - Northeastern Athletic Conference
 - Northern Illinois Conference (NIC-10)
 - Northern Lake County Conference
 - Northwest Upstate Illini Conference (contains two divisions)
 - Pike County Conference
 - Prairieland Conference
 - River Valley Conference
 - Sangamo Conference
 - South Central Conference (Illinois)
 - South Egyptian Conference
 - South Seven Conference
 - South Suburban Conference
 - Southern Illinois River-to-River Conference (with Mississippi and Ohio River divisions)
 - Southland Athletic Conference
 - Southwest Prairie Conference
 - Southwest Suburban Conference
 - Southwestern Conference
 - Three Rivers Conference
 - Tomahawk Conference (Illinois)
 - Tri-County Conference
 - Upstate Eight Conference
 - Vermilion Valley Conference
 - West Central Conference
 - West Suburban Conference (contains two divisions)
 - Western Big 6 Conference
 - Western Illinois Valley Conference (contains two divisions)
 
Former Conferences
- Ambraw Valley Conference (1945-1955)
 - Big 8 (1980-1995)
 - Big Rivers Conference (football-only) (1999-2012)
 - Bi-County Conference (1917-1919)
 - Bi-County Conference (1970s-1998)
 - Blackhawk Conference (West) (1934-1990)
 - Blackhawk Conference (North) (1947-1972)
 - Bureau Valley Conference (1970s-1990s)
 - Capitol Conference (1964-1982)
 - Cenois Conference (1963-1969)
 - Central Conference (1956-1958)
 - Central Egyptian Conference (1929-1940)
 - Chicagoland Prep Conference (1961-1969)
 - Coal Belt Conference (1946-1956)
 - Cook County High School League (1889–1913)
 - Corn Belt Conference (1950–2017)
 - Des Plaines Valley Conference (1963-1985)
 - East Okaw Conference (1981-1995)
 - Eastern Illinois Conference (1952-1969)
 - Four Rivers Conference (2000-2006)
 - Fox Valley Conference (1952-1966)
 - Gateway East Conference (1979-1983)
 - Greater Midwestern Conference (1983-1986)
 - Heartland Conference (Illinois) (1978-1982)
 - Heart of Illinois Conference (1970s) (1972–1978)
 - Illini Central Conference (1985-1998)
 - Illini 8 Conference (1966-1981)
 - Illini Valley Conference (North Central) (1970-1972)
 - Illini Valley Conference (South Central) (1928-1973)
 - Illio Conference (1952-1975)
 - Illowa Conference (1952-1974)
 - Indian Valley Conference (1976-1994)
 - Iroquois Conference (1970s-1980s)
 - Kane County Conference (????-1917)
 - Kankakee Valley Conference (1950-1979)
 - La Moine Valley Conference (1952-1967)
 - Little 6 Conference (1952–1975)
 - Little 7 Conference (1921–1995)
 - Little 8 Conference (North Central) (1921–1975)
 - Little 8 Conference (Far North) (1920s–1980)
 - Little 8 Conference (Northeast) (1919–19??)
 - Little 8 Conference (Northwest) (1918–192?)
 - Little 8 Conference (Southwest) (????–????)
 - Little Egypt Conference (1960s-1970s)
 - Little Five Conference (1923-1939)
 - Little Four Conference (19??'s-1948)
 - Meridian Conference (Central Illinois) (1959-1993)
 - Meridian Conference (Northern Illinois) (????-????)
 - Metro Catholic Conference (1960-1965)
 - Mid Northern Confernce (1972-1995)
 - Mid-South Conference (1983-2008)
 - Mid-State Conference (1944-1997)
 - Mid-State Six Conference (196?-2015)
 - Midwest Conference (1948-1970)
 - Midwestern Conference (1952-1970)
 - Mississippi Valley Conference (1957-1968)
 - New Salem Conference
 - North Central Illinois Conference (1929-2011)
 - North Egypt Conference (1938-2003)
 - North Shore Conference (1904-1914)
 - North Six Conference (1939-1946)
 - Northern Illinois Big 12 Conference (2010-2018)
 - Northwest Conference (1963-1974)
 - Northwest Illinois Conference (NWIC) (1974-1996)
 - Northwest 7 Conference (1972-1973)
 - Northwest 8 Conference (1977-1990)
 - Northwest Suburban Conference (1925-1997)
 - Okaw Valley Conference (1950s-2017)
 - Olympic Conference (1976-2010)
 - PMSC Conference (1961-1973)
 - Prairie State Conference (1985-????)
 - Quad Cities Metro Conference (1950-1977)
 - River Trails Conference (1990-1995)
 - Rock River (Valley) Conference (1924-1948)
 - Route 72 Conference (1952-1972)
 - Sangamon Valley Conference (1948-2021)
 - SHARK Conference (1946-1982)
 - SICA — (South Inter-Conference Association, dissolved 2006)
 - Southeast Suburban Conference (1962-1972)
 - Southern Conference (IHSA) (????-????)
 - Southern Illini Conference (1957-1974)
 - Southern Illini Conference (1986-1993)
 - Southwest Egyptian Conference (????-1993)
 - Spoon River Conference (1959-1985)
 - Stephenson County Conference (1958-1963) (Renamed "Northwest Illinois Conference")
 - Suburban Catholic Conference (1960-1973)
 - Suburban Catholic Conference (2009-2015)
 - Suburban League (1913–1975)
 - Suburban Prairie Conference (1995-2005)
 - SWANI Conference (1946-1953)
 - Tollway Athletic Conference
 - Trailblazer Conference (1982-1984)
 - Tri State Conference (1932-1935)
 - Two Rivers Conference (19??-1958)
 - United Conference (1958-1963)
 - Upstate Illini Conference (1974-1976)
 - Upstate Illini Conference (1991-2000)
 - US Grant Conference (1950-1958)
 - Vermilion Valley Conference (1950-1981)
 - Wauseca Conference (1928-1989)
 - West Prairie Trail Conference
 - Western Area Conference (1974-1996)
 - Western Athletic Conference (1908-1921)
 - Western Sun Conference (2006-2010)
 - Western Suburban Athletic Conference (1903-1910)
 - Western Suburban Catholic Conference (1974-1988)
 - Wilco Conference (1959-1973)
 - Wil-Ro-Kee Conference (1954-1959) (Renamed "Kankakee Valley Conference" in 1960)
 
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