Eurocup Basketball 2009–10 qualifying round was the qualifying round for the 2009-10 Eurocup season. There were 16 teams that played two games each. The winners went on to the group stage.
Bracket
| Team #1 | Agg. | Team #2 | 1st leg | 2nd leg | 
|---|---|---|---|---|
| MyGuide Amsterdam  | 112-141 |  Dynamo Moscow | 64 - 63 | 48-78 | 
| Dexia Mons-Hainaut .svg.png.webp) | 139-142 |  Valencia Basket | 78 - 63 | 61-79 | 
| WBC Kraftwerk Wels  | 155-169 |  Beşiktaş Cola Turka | 74 - 69 | 81-100 | 
| BK VEF Rīga  | 158-168 |  Panellinios | 79 - 94 | 79-74 | 
| Brose Baskets Bamberg  | 129-128 |  KK Budućnost | 64 - 61 | 65-67 | 
| BC Donetsk  | 150-153 |  Bizkaia Bilbao Basket | 71 - 63 | 79-90 | 
| APOEL Nicosia  | 149-150 |  BancaTercas Teramo | 77 - 63 | 62-77 | 
| Chorale Roanne Basket  | 162-169 |  Hapoel Jerusalem | 83 - 81 | 79-88 | 
First leg
| October 20, 2009 | 
|  MyGuide Amsterdam | 64–63 |  Dynamo Moscow | 
| Pts: Rodgers, Voorn 17 Rebs: Krabbendam 8 Asts: Rodgers 6 | Pts: Monia 13 Rebs: Monia 8 Asts: Bykov 4 | 
| Sporthallen Zuid, Amsterdam | 
| October 20, 2009 | 
| .svg.png.webp) Dexia Mons-Hainaut | 78–63 |  Valencia Basket | 
| Pts: Torbert 25 Rebs: Ebong 12 Asts: Torbert 6 | Pts: de Colo 21 Rebs: de Colo 7 Asts: Martínez 5 | 
| October 20, 2009 | 
|  WBC Kraftwerk Wels | 74–69 |  Beşiktaş Cola Turka | 
| Pts: Conley 25 Rebs: Conley 16 Asts: Moore 6 | Pts: Özer 20 Rebs: Chatman, Baxter 7 Asts: Chatman 4 | 
| October 19, 2009 | 
|  BK VEF Rīga | 79–94 |  Panellinios | 
| Pts: Aleksejevs 21 Rebs: Aleksejevs 6 Asts: Labuckas 6 | Pts: Smith 25 Rebs: Johnsen 8 Asts: Xanthopoulos 7 | 
| October 20, 2009 | 
|  BC Donetsk | 71–63 |  Bizkaia Bilbao Basket | 
| Pts: Perry 18 Rebs: Drozdov 8 Asts: Tucker 5 | Pts: Blūms 12 Rebs: Mumbrú 6 Asts: four players 1 | 
| October 20, 2009 | 
|  APOEL Nicosia | 77–63 |  BancaTercas Teramo | 
| Pts: Heath 22 Rebs: Phillips 8 Asts: Heath 6 | Pts: Diener 16 Rebs: Diener 7 Asts: three players 2 | 
| October 20, 2009 | 
|  Chorale Roanne Basket | 83–81 |  Hapoel Jerusalem | 
| Pts: Noel 26 Rebs: Nsonwu 10 Asts: Diabate 9 | Pts: Simmons 20 Rebs: Pinkney 9 Asts: Thompson, Simmons 5 | 
| October 21, 2009 | 
|  Brose Baskets | 64–61 |  KK Budućnost | 
| Pts: Brown 20 Rebs: Brown, Jacobsen 6 Asts: three players 2 | Pts: Dragičević 23 Rebs: Dragičević 8 Asts: Šehović 5 | 
Second leg
| October 27, 2009 | 
|  Panellinios | 74–79 |  BK VEF Rīga | 
| Pts: Johnsen 22 Rebs: Smith 8 Asts: Haralabidis 3 | Pts: Renfroe, Bankevics 23 Rebs: Šeļakovs 6 Asts: Mažeika 6 | 
Panellinios won by an aggregate score of 168-158 and advanced to the group stage.
| October 27, 2009 | 
|  Beşiktaş Cola Turka | 100–81 |  WBC Kraftwerk Wels | 
| Pts: Chatman 34 Rebs: Chatman 8 Asts: Chatman 9 | Pts: Conley 24 Rebs: Lamesic 11 Asts: Conley, Meacham 5 | 
Beşiktaş Cola Turka won by an aggregate score of 169-155 and advanced to the group stage.
| October 27, 2009 | 
|  Valencia Basket | 79–61 | .svg.png.webp) Dexia Mons-Hainaut | 
| Pts: Martínez 18 Rebs: Claver 8 Asts: Claver, Nielsen 3 | Pts: Coleman 12 Rebs: three players 5 Asts: Costner 2 | 
Valencia Basket won by an aggregate score of 142-139 and advanced to the group stage.
| October 27, 2009 | 
|  Dynamo Moscow | 78–48 |  MyGuide Amsterdam | 
| Pts: four players 15 Rebs: Monia 10 Asts: Monia, Khvostov 4 | Pts: Rodgers, Voorn 17 Rebs: Krabbendam 8 Asts: Rodgers 6 | 
Dynamo Moscow won by an aggregate score of 141-112 and advanced to the group stage.
| October 27, 2009 | 
|  BancaTercas Teramo | 77–62 |  APOEL Nicosia | 
| Pts: Jones 16 Rebs: Jurak 7 Asts: Hoover 6 | Pts: Sims 28 Rebs: Cisse 12 Asts: King 2 | 
BancaTercas Teramo won by an aggregate score of 150-149 and advanced to the group stage.
| October 28, 2009 | 
|  Hapoel Jerusalem | 88–79 |  Chorale Roanne Basket | 
| Pts: Simmons 22 Rebs: Hunter 6 Asts: Ohayon 6 | Pts: Nsonwu 21 Rebs: Page 8 Asts: Pellin 5 | 
Hapoel Jerusalem won by an aggregate score of 169-162 and advanced to the group stage.
| October 28, 2009 | 
|  KK Budućnost | 67–65 |  Brose Baskets | 
| Pts: Gordić 19 Rebs: Simonović 8 Asts: Jeretin 2 | Pts: Suput 15 Rebs: Roberts, Goldsberry 6 Asts: five players 2 | 
Brose Baskets won by an aggregate score of 129-128 and advanced to the group stage.
| November 3, 2009 | 
|  Bizkaia Bilbao Basket | 90–79 |  BC Donetsk | 
| Pts: Banić 28 Rebs: Moïso 6 Asts: Warren 4 | Pts: Perry 18 Rebs: Drozdov 8 Asts: Tucker 5 | 
Bizkaia Bilbao Basket won by an aggregate score of 153-150 and advanced to the group stage.