William Babington may refer to:
- William Babington (academic), Vice-Chancellor of Oxford University, 1441–1443
- William Babington (justice) (c. 1370–1454), English lawyer and judge
- William Babington (physician) (1756–1833), Anglo-Irish physician and mineralogist
- William Babington (East India Company officer), Anglo-Irish officer
See also
- W. B. Maxwell (William Babington Maxwell, 1866–1938), British novelist
- William Babbington, fictional Royal Navy captain in the novels of Patrick O'Brian
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