Mohammad Yusuf, Muhammad Yousuf and other spellings, may refer to:
Politicians
- Mohammad Yusuf (politician), prime minister and foreign minister of Afghanistan
 - Mohammad Yousef, a governor of Daykundi of Province, Afghanistan
 - Muhammad Yusuf Abdullah Haroon, politician from Sindh, Pakistan.
 - Mohamed Yusuf Haji (born 1940), Somali politician and Kenyan Member of Parliament
 
Sports players
- Mohamed Yusuf (athlete) (born 1968), Indonesian Olympic sprinter
 - Mohammad Yousuf (cricketer) born 1974), Pakistani former international cricketer.
 - Mohammed Yousuf (snooker player), Pakistani former snooker player
 
Others
- Mohammed Yusuf (Boko Haram), Nigerian sect leader of Boko Haram (1970-2009)
 - Mohamed Yusuf (1876–1965), Indian businessman
 - Mohammad Yousuf Azraq, Afghanistan historian and writer
 - Muhammad Yusuf Kandhalawi (1917–1965), Indian Muslim scholar, leader of the Tablighi Jamaat
 - Muhammad Yousuf Khan (1922–2021), also known as Dilip Kumar, Indian film actor
 - Yusaf Khan (general), Muhammad Yusaf Khan, former Vice Chief of Pakistan Army Staff
 
See also
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