MLL may refer to:
- Major League Lacrosse
 - Malua Bay language (ISO 639-3: mll), spoken in Malekula, Vanuatu
 - Marshall Don Hunter Sr. Airport (IATA: MLL), in Marshall, Alaska
 - Mayor Lori Lightfoot, mayor of Chicago
 - Morel-Lavallée lesion
 - An enzyme encoded by the KMT2A gene
 
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