Lobe is a surname. Notable people with the surname include:
- Adolf Lobe (1860–1939), German jurist and member of the Reichstag in the Weimar Republic
- Bill Lobe (1912–1969), American baseball player and coach
- Jim Lobe (born 1949), American journalist
- Kārlis Lobe (1895–1985), Latvian collaborationist with the Nazis
- Mira Lobe (1913–1995), Austrian author
- Robert Lawrance Lobe (born 1945), American sculptor
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