This is an alphabetical list of Welsh women.
A
- Jane Aaron (born 1951), literature scholar, researcher, non-fiction writer
 - Janet Ackland (born 1938), bowler
 - Helen Adams (born 1978), television personality
 - Sian Adey-Jones (born 1957), model, actress
 - Wendy Albiston (born 1969), actress
 - Jessica Allen (born 1989), racing cyclist
 - Jan Anderson (born 1974), actress
 - Elizabeth Andrews (1882–1960), suffragist, writer
 - Josie d'Arby (born 1972), actress, writer, television presenter
 - Jane Arden (1927–1982), film director, actress, screenwriter, playwright, poet
 - Kim Ashfield (born 1959), model
 - Laura Ashley (1925–1985), fashion designer
 - Tiffany Atkinson (born 1972), poet, educator
 - Trezza Azzopardi (born 1961), widely translated novelist, short story writer, author of The Hiding Place
 - Janet Ackland (born 1938), bowler
 
B
- Emilia Baeyertz (1842–1926), Christian missionary
 - Mary Balogh (born 1944), Welsh-Canadian historical novelist
 - Iona Banks (1920–2008), actress
 - Elinor Barker (born 1994), racing cyclist
 - Lorraine Barrett (born 1950), politician
 - Rachel Barrett (1874–1953), suffragette, newspaper editor
 - Shirley Bassey (born 1937), singer
 - Anne Beale (1816–1900), popular novelist, poet, children's writer
 - Remy Beasley (active since 2015), actress
 - Eirlys Bellin (active since 2000s), actress
 - Anna Maria Bennett (c.1750–1808), novelist
 - Jane Brereton (1685–1740), English-language poet
 - Tara Bethan (born 1984), actress, singer
 - Bridget Bevan (1698–1779), educationalist and public benefactor
 - Ruth Bidgood (born 1922), poet
 - Joyce Bland (1906–1963), film actress
 - Cate Le Bon (born 1983), singer-songwriter
 - Di Botcher (active since 1986), actress
 - Ffion Bowen (born 1991), rugby union player
 - Nan Braunton (1895–1978), actress
 - Jane Brereton (1685–1740), poet, contributor to The Gentleman's Magazine
 - Becky Brewerton (born 1982), golfer
 - Rhoda Broughton (1840–1920), novelist, short story writer
 - Mia Arnesby Brown (1867–1931), painter
 - Eleanor Bufton (1842–1893), actress
 - Fanny Bulkeley-Owen (1845–1927), historian, writer
 - Frances Bunsen (1791–1876), painter, writer
 - Eleanor Bufton (active since 2004), actress
 
C
- Betsi Cadwaladr (1789–1860), nurse in the Crimean War
 - Julia Callan-Thompson (1944–1979), model, designer, socialite
 - Saint Callwen (6th century), Christian saint
 - Saint Canna (6th century), nun
 - Nia Caron (active since 1980s), Welsh-language actress
 - Emma Catherwood (born 1981), actress, model
 - Emma Catherwood (1968), actress
 - Catrin ferch Gruffudd ap Hywel (fl. 1555), poet
 - Jane Cave (c.1754–1812), English-language poet
 - Christine Chapman (born 1956), politician
 - Brenda Chamberlain (1912–1971), artist, poet
 - Kara Chesworth (born 1972), racing cyclist
 - Shefali Chowdhury (born 1988), actress
 - Sybil Christopher (1929–2013), actress, theatre director
 - Charlotte Church (born 1986), singer
 - Gillian Clarke (born 1937), poet, playwright, translator, broadcaster
 - Hafina Clwyd (1936–2011), educator, writer
 - Grace Coddington (born 1941), fashion writer, director of Vogue, memoirist
 - Lu Corfield (active since 2012), actress
 - Nicole Cooke (born 1983), racing cyclist
 - Glenys Cour (born 1924), painter, stained glass artist
 - Shân Cothi (born 1965), singer, actress
 - Margaret Courtenay (1923–1996), actress, singer, entertainer
 - Elinor Crawley (born 1991), actress
 - Leila Crerar (active since 1980s), actress
 - Jasmine Cresswell (born 1941), best selling novelist
 - Katie Curtis (born 1988), road and track cyclist
 
D
- Fflur Dafydd (born 1978), novelist, playwright, poet, singer, writes in Welsh and English
 - Hannah Daniel (born 1986), actress
 - Lisa Lee Dark (born 1981), opera singer, voice actress
 - Jennifer Daniel (born 1936), film actress
 - Alexa Davies (born 1995), actress
 - Catherine Glyn Davies (1926–2007), historian, translator
 - Clara Novello Davies (1861–1943), singer and conductor
 - Deddie Davies (born 1938), actress
 - Deborah Kay Davies, contemporary poet, novelist, educator
 - Edna Davies (1905–1969), actress
 - Gwendoline Davies (1882–1951), philanthropist, arts patron
 - Jocelyn Davies (born 1959), politician
 - Karen Davies (born 1965), golfer
 - Llewela Davies (1871–1952), pianist and composer
 - Lynette Davies (1948–1993), actress
 - Margaret Davies (fl. 1700s), poet, scribe
 - Margaret Davies (1884–1963), arts patron
 - Mary Davies (1855–1930), mezzo-soprano
 - Mary Davies (1846–1882), poet
 - Nina Davies (born 1974), racing cyclist
 - Phoebe Davies (1864–1912), Welsh-born American actress
 - Rachel Davies (1846–1915), lecturer and evangelist preacher
 - Rose Davies (1882–1958), teacher, activist, politician
 - Valerie Davies (1912–2001), swimmer
 - Rebecca De Filippo (born 1994), rugby union player
 - Cherry Dee (born 1987), model
 - Sophie Dee (born 1984), pornographic actress
 - Jen Delyth (born 1962), specializing in Celtic symbolism
 - Myrtle Devenish (1913–2007), actress
 - Marina Diamandis (born 1985), singer-songwriter
 - Amy Dillwyn (1845–1935), novelist, industrialist
 - Thereza Dillwyn Llewelyn, photographer, astronomer
 - Leila Crerar (born 1984), actress
 - Aimée Ann Duffy (born 1984), singer, songwriter
 - Ruth Dunning (1911–1983), actress
 
E
- Aimee-Ffion Edwards (born 1987), actress
 - Mary Anne Edmunds (1813–1858), educator
 - Donna Edwards (born 1963), actress
 - Dorothy Edwards (1903–1934), novelist, short story writer
 - Fanny Winifred Edwards (1876–1959), schoolteacher, children's writer, dramatist
 - Maudie Edwards (1906–1991), actress, singer, comedian
 - Rhian Edwards (active from 2000s), poet
 - Sarah Edwards (1881–1965), Welsh born American actress
 - Sara Edwards (born 1961), broadcast journalist, television presenter
 - Elen Egryn (1807–1897), Welsh-language poet
 - Menna Elfyn (born 1952), Welsh-language poet, playwright, columnist, editor, poetry widely translated
 - Gillian Elisa (born 1953), actress, singer, comedian
 - Amy Evans (1884–1983), soprano, actress
 - Peg Entwistle (1908–1932), actress
 - Claire Evans (born 1983), model
 - Christine Evans (born 1943), poet
 - Elen Evans (born 1985), rugby union player
 - Jennifer Evans (active since 2004), actress
 - Kate Williams Evans (1866–1961), suffragette and activist for women's rights
 - Laura Evans (active since 1990s), actress, singer, songwriter
 - Margiad Evans (1909–1958), poet, novelist
 - Mary Evans (1735–1789), sect leader
 - Maxine Evans (born 1966), actress
 - Sophie Evans (born 1993), singer, actress
 - Laura Evans-Williams (1883–1944), soprano
 
F
- Pam Ferris (born 1948), actress
 - Catrin Finch (born 1980), harpist
 - Ilora Finlay, Baroness Finlay of Llandaff (born 1949), physician, politician
 - Catherine Fisher (born 1957), novelist, poet, broadcaster
 - Connie Fisher (born 1983), actress, singer
 - Laura Ford (born 1961), sculptor
 - Rosemarie Frankland (1943–2000), actress, model
 - Jane Freeman (born 1921), actress
 - Jocelyn Freeman (born 1986), pianist
 - Kathleen Freeman (1897–1959), classicist
 - Liz Fuller (born 1975), television presenter, actress, model
 
G
- Menna Gallie (1919–1990), novelist, translator
 - Valerie Ganz (1936–2015), painter
 - Jacqui Gasson (active since 1988), lord mayor of Cardiff
 - Beti George (born 1939), journalist and broadcaster
 - Seren Gibson (born 1988), model
 - Sian Gibson (born 1976), actress, writer
 - Olive Gilbert (1898–1981), singer, actress
 - Annabel Giles (born 1950), broadcaster, best selling novelist, actress
 - Julia Gillard (born 1961), Australian prime minister
 - Mary Dilys Glynne (1895–1991), plant pathologist, mountaineer
 - Julie Gould (born 1989), swimmer
 - Helen Grace (active since 2004), film director
 - Janice Gregory (born 1955), politician
 - Sara Gregory (born 1986), actress
 - Clare Greenwood (born 1958), cyclist
 - Elizabeth Griffith (1727–1793), writer
 - Helen Griffin (active since the 1980s), actress, writer
 - Ann Griffiths (1776–1805), religious poet, hymn writer
 - Lesley Griffiths (born 1960), politician
 - Amy Guy (born 1983), model
 - Lady Charlotte Guest (1812–1895), aristocrat and translator
 - Bethan Gwanas, pen name of Bethan Evans (born 1962), Welsh-language novelist, children's writer
 - Saint Gwenfyl (fl. 6th century), Christian saint
 - Lowri Gwilym (1954––2010), television and radio producer
 - Eirwen Gwynn (1916–2007), nationalist, writer, teacher and scientist
 - Gwenllian ferch Gruffydd (1097–1137), Princess Consort of Deheubarth
 - Gwenllian of Wales (1282–1337), daughter of Llywelyn ap Gruffudd
 - Gwerful Fychan (fl. 1420–1490), Welsh-language poet
 - Denise Gyngell (born 1961), singer, actress, model
 
H
- Cerys Hale (born 1993), rugby union player
 - Holly Hale (born 1990), model
 - Augusta Hall, Baroness Llanover (1802–1896), arts patron
 - Nina Hamnett (1890–1956), painter
 - Doris Hare (1905–2000), actress, singer
 - Mali Harries (born c.1976), actress
 - Edwina Hart (born 1957), politician
 - Ann Hatton (1764–1838), novelist
 - Myfanwy Haycock (1913–1963), poet, artist, broadcaster
 - Angela Hazeldine (born 1981), actress, musician
 - Venissa Head (born 1956), track and field athlete
 - Anneliese Heard (born 1981), cyclist
 - Georgia Henshaw (born 1993), actress
 - Deirdre Hine (born 1937), physician
 - Sally Hodge (born 1966), cyclist
 - Frances Hoggan (1843–1927), physician, first female doctor registered in Wales
 - Sophie Holland (active since 2000s), actress
 - Karen Holford (active since 1990), engineer and professor
 - Nichola Hope (born 1975), painter, writer, silhouettist
 - Sarah Hope (born 1975), twin sister of Nichola, painter, writer, actress
 - Mary Hopkin (born 1950), singer
 - Sally El Hosaini (born 1976), film director, writer
 - Ray Howard-Jones (1903–1996), Berkshire-born artist who lived in Penarth from an early age
 - Ann Harriet Hughes (1852–1910), Welsh-language novelist, poet
 - Ellen Hughes (1867–1927), Welsh-language writer, suffragist, temperance reformer
 - Megan Hughes (born 1977), cyclist
 - Nerys Hughes (born 1941), actress
 - Judith Humphreys (born 1988), actress
 - Ellen Hunter (born 1968), cyclist
 - Ruth Hussey, from 2012 to 2014: Chief Medical Officer for Wales
 - Jane Hutt (born 1949), politician
 - Joan Hutt (1913–1985), Hertfordshire-born painter who moved to live in North Wales in 1949
 - Emily Huws (born 1942), Welsh-language children's writer
 
I
- Elisabeth Inglis-Jones (1900–1994), novelist
 - Norah Isaac (1915–2003), Welsh-language short story writer, playwright, travel writer
 
J
- Katrina Jacks (born 1986), rower
 - Angharad James (1677–1749), poet and harpist
 - Becky James (born 1991), cyclist
 - Irene James (born 1952), politician
 - Jynine James (born 1972), actress, singer
 - Maria James (1793–1868), Welsh-born American poet
 - Stephanie James (born 1985), actress
 - Kate Jarman (born 1980), actress
 - Ruth Jên (born 1964), painter, illustrator
 - Katherine Jenkins (born 1980), singer
 - Kathryn Jenkins (1961–2009), scholar and writer of Welsh hymns
 - Joan, Lady of Wales (c.1191–1237), wife of Llywelyn the Great
 - Gwen John (1876–1939), painter
 - Margaret John (1926–2011), actress
 - Glynis Johns (1923–2024), actress, pianist, singer
 - Alex Jones (born 1977), television presenter
 - Alice Gray Jones (1852–1943), writer, editor
 - Ann Jones (born 1953), politician
 - Della Jones (born 1946), singer
 - Dora Herbert Jones (1890–1974), administrator and singer
 - Elin Jones (born 1966), politician
 - Elizabeth Jane Louis Jones (1889–1952), scholar
 - Frances Môn Jones (1919–2000), harpist and teacher
 - Gwyneth Jones (born 1936), singer
 - Iona Jones (active since 1986), broadcaster, television executive
 - Louise Jones (born 1963), cyclist
 - Mai Jones (1899–1960) songwriter, entertainer and radio producer
 - Mary Jones (1896–1990), actress
 - Mary Lloyd Jones (born 1934), painter, printmaker
 - Mary Vaughan Jones (1918–1983), children's writer, teacher
 - Ruth Jones (born 1966), actress, writer
 - Ruth Jones, Labour Party politician
 - Sue Jones-Davies (born 1949), actress, singer
 
K
- Katheryn of Berain (1534–1591), noblewoman
 - Gwyneth Keyworth (active since 2009), actress
 - Nyree Kindred (born 1980), swimmer
 - Christine Kinsey (born 1942), painter
 
L
- Margaret Lacey (1910–1989), actress, ballet teacher
 - Kate Lambert (active since 2000s), model, fashion designer
 - Sarah Lark (born 1983), singer, actress
 - Lisa Lazarus (born 1987), model, actress
 - Nancy Lee (born 1970), Welsh-born short story writer, novelist, now in Canada
 - Ruby Levick (c.1872–1940), sculptor
 - Donna Lewis (born 1973), singer, musician
 - Eiluned Lewis (1900–1979), novelist, poet, journalist
 - Emmeline Lewis Lloyd (1827–1913), mountaineer
 - Gwyneth Lewis (born 1959), Welsh-language poet, national poet of Wales, also writes in English
 - Princess Lilian, Duchess of Halland (1915–2013), fashion model, Swedish princess
 - Danielle Lineker (born 1979), actress, model
 - Betsan Llwyd, actress, since 2012, Arts Director of Bara Caws
 - Margaret Lloyd (1709–1762), Moravian missionary
 - Mary Lloyd (1819–1896), sculptor
 - Mary Lloyd Jones (born 1934), painter
 - Sian Lloyd (born 1972), news presenter
 - Siân Lloyd (born 1958), weather presenter
 - Angharad Llwyd (1780–1866), antiquary
 - Eirian Llwyd (1951–2014), artist
 - Martha Llwyd (1766–1845), poet, hymnist
 - Jemma Lowe (born 1990), swimmer
 
M
- Georgia Mackenzie (born 1973), actress
 - Margaret Mackworth, 2nd Viscountess Rhondda (1883–1958), businesswoman and suffragette
 - Ruth Madoc (born 1943), actress, singer
 - Sharon Maguire (born 1960), film director
 - Ruth Manning-Sanders (1886–1988), poet, children's writer
 - Edith Mansell Moullin (1859–1941), suffragist
 - Deborah Manship (born 1953), actress
 - Ursula Masson (1945–2008), educator, literature researcher, non-fiction writer
 - Cerys Matthews (born 1969), singer, songwriter, broadcaster, writer
 - Gwerful Mechain (c.1460–1502), early Welsh-language poet
 - Nia Medi, since 2005, Welsh-language novelist, actress
 - Leila Megàne (1891–1960), opera singer
 - Sandy Mewies (born 1950), politician
 - Dorothy Miles (1931–1993), poet, wrote in English and sign language
 - Ruby Miller (born 1992), cyclist
 - Tracey Moberly (born 1964), multidisciplinary artist
 - Ann Moray (1909–1981), novelist, short story writer, singer
 - Diana Morgan (1908–1996), playwright, screenwriter
 - Elaine Morgan (1920–2013), playwright, non-fiction writer
 - Gwenllian Elizabeth Fanny Morgan (1852–1939), mayor, antiquarian
 - Helen Morgan (born 1952), model
 - Kate Alicia Morgan (born 1983), model, actress
 - Sally Moore (born 1962), painter
 - Beth Morris (born 1949), actress
 - Siwan Morris (born 1976), actress
 - Moelona, pen name of Elizabeth Mary Jones (1877–1953), Welsh-language novelist, children's writer, translator
 - Becky Morgan (born 1974), golfer
 - Chloe-Beth Morgan (born 1986), model
 - Elaine Morgan (1920–2013), non-fiction writer on anthropology, playwright, columnist
 - Elaine Morgan (born 1960), singer
 - Elena Puw Morgan (1900–1973), Welsh-language novelist, children's writer
 - Eluned Morgan (1870–1938), Welsh-language author from Patagonia, travel writer, non-fiction writer
 - Kate Alicia Morgan (born 1983), model
 - Sharon Morgan (born 1949), actress
 - Kay Morley-Brown (born 1963), athlete
 - Kelly Morgan (born 1975), badminton player
 - Penelope Mortimer (1918–1999), journalist, biographer, novelist
 - Sophie Moulds (born 1992), model
 - Wendy Mulford (born 1941), poet, feminist
 - Catherine Murphy (born 1975), athlete
 - Eve Myles (born 1978), actress
 
N
- Lynne Neagle (born 1968), politician
 - Liz Neal (born 1973), artist based in London
 - Mary Edith Nepean (1876–1960), writer
 - Mavis Nicholson (born 1930), writer, broadcaster
 - Kimberley Nixon (1985), actress
 
O
- Pixie O'Harris (1903–1991), Welsh-born Australian artist, poet, autobiographer, illustrator
 - Tessie O'Shea (1913–1997), stand-up comedian
 - Angharad ferch Owain (1065–1162), queen of Gwynedd
 - Bethan Ellis Owen (active since 1990s), actress
 - Lucy Owen (born 1970), television news reader
 - Mary Owen (1796–1875), hymnwriter
 - Meg Wynn Owen (born 1939), actress
 - Morfydd Llwyn Owen (1891–1918), composer, pianist and singer
 
P
- Suzanne Packer (born 1958), actress
 - Joanna Page (born 1978), actress
 - Lisa Palfrey (active since 1990s), actress
 - Davinia Palmer (born 1980), television presenter, voice-over artist, now in the United States
 - Stephanie Parker (1987–2009), actress
 - Molly Parkin (born 1932), painter, novelist, journalist
 - Blanche Parry (1507–1590), personal attendant of Queen Elizabeth I
 - Sarah Winifred Parry (1870–1953), writer
 - Caryl Parry Jones (born 1958), singer, songwriter, actress, composer
 - Amy Parry-Williams (1910–1988), singer, writer
 - Karen Paullada (active since 2000s), actress
 - Sarah Payne, probation executive
 - Allison Pearson (born 1960), journalist, writer
 - Jessie Penn-Lewis (1861–1927), evangelist, religious writer, magazine publisher
 - Anne Penny (1729–1784), poet
 - Mary Penry (1735–1804), Moravian sister in Pennsylvania
 - Kelly-Louise Pesticcio (born 1974), beauty pageant winner
 - Pauline Peters (born 1896), actress
 - Pascale Petit (born 1953), poet
 - Karen Paullada (active since 2009), actress
 - Carys Phillips (born 1992), rugby union player
 - Lauren Phillips (born 1981), actress
 - Mary Elizabeth Phillips (1875–1956), medical doctor
 - Siân Phillips (born 1933), actress
 - Jayne Pierson (active since 2009), fashion designer
 - Eleanor Pilgrim (born 1977), golfer
 - Katherine Philips (1632–1664), poet, translator
 - Victoria Plucknett (born 1953), actress
 - Annie Powell (1906–1986), politician
 - Shona Powell Hughes (born 1991), rugby union player
 - Angharad Price, novelist since 1999, academic
 - Dilys Price (1932–2020), educator and parachutist
 - Maria Pride (born 1970), actress
 - Myfanwy Pryce (1890–1976), novelist
 
Q
- Mary Quant (born 1934), fashion designer
 
R
- Allen Raine, pen name of Anne Adalisa Beynon Puddicombe (1836–1908), novelist, wrote in English and Welsh
 - Elizabeth Randles (c.1801–1829), harpist and pianist
 - Susannah Jane Rankin (1897–1989), minister, educator, translator
 - Helen Raynor (born 1972), television screenwriter, script editor, playwright
 - Cara Readle (born 1991), actress
 - Angharad Rees (1944–2012), actress
 - Deryn Rees-Jones, since 1994, poet, essayist
 - Dorothy Rees (1898–1987), Labour Party politician
 - Sarah Jane Rees (1839–1916), teacher, poet, temperance campaigner
 - Shelley Rees (active since 1990s), actress
 - Yvette Rees (active in the 1960s and 1970s), actress
 - Sian Reese-Williams (born 1981), actress
 - Nicola Reynolds (born 1972), actress
 - Beti Rhys (1907–2003), bookseller and author
 - Elen Rhys (active since 2011), actress
 - Nest ferch Rhys (1085–1136), princess of Deheubarth
 - Shani Rhys James (born 1953), Australia-born painter, moved to Wales after graduation
 - Mandy Rice-Davies (1944–2014), model, showgirl, writer
 - Ceri Richards (1903–1971), painter
 - Nansi Richards (1888–1979), harpist
 - Rosalind Richards (active since 2000s), actress
 - Mandy Rice-Davies (born 1986), actress
 - Alexandra Roach (born 1987), actress
 - Beth Robert (active since 1987), actress
 - Kate Roberts (1891–1985), leading Welsh-language novelist, short story writer
 - Nia Roberts (born 1972), actress
 - Rachel Roberts (1927–1980), actress
 - Sally Roberts Jones (born 1935), poet, biographer
 - Nia Roberts (born 1979), actress
 - Beth Robert (born 1979), actress
 - Philippa Roles (born 1978), discus thrower
 - Ceinwen Rowlands (1905–1983), soprano
 - Jane Helen Rowlands (1891–1955), scholar, missionary
 - Bernice Rubens (1923–2004), novelist, author of The Elected Member
 - Joan Ruddock (born 1943), politician
 
S
- Saint Non (c. 5th–6th century), saint, mother of Saint David
 - Rhian Samuel (born 1944), composer
 - Molly Scott Cato (born 1963), politician, economist
 - Lisa Scott-Lee (born 1975), singer
 - Helen Sear (born 1955), photographic artist
 - Carole Seymour-Jones (born 1963), biographer, columnist, literary non-fiction writer
 - Caroline Sheen (born 1976), actress
 - Sarah Siddons (1755–1831), actress
 - Dorothy Simpson (born 1933), mystery novelist, crime-fiction writer
 - Karen Sinclair (born 1952), politician
 - Caroline Skeel (1872–1951), historian
 - Sylvia Sleigh (1916–2010), Welsh-born American painter
 - Dorothy Squires (1915–1998), singer
 - Florence Smithson (1884–1936), actress, singer
 - Emma Stansfield (born 1978), actress
 - Alison Statton (born 1959), singer
 - Irene Steer (1889–1947), swimmer
 - Jaci Stephen (born 1958), journalist, broadcaster, actress, writer
 - Catrin Stewart (born 1988), actress
 - Sara Sugarman (born 1962), actress, film director
 - Jessica Sula (born 1994), actress
 - Jennifer Sullivan (born 1945), children's writer, critic
 - Rosie Swale-Pope (born 1946), marathon runner, non-fiction writer
 - Alia Syed (born 1964), Swansea-born artist and filmmaker, now living and working in London
 
T
- Myfanwy Talog (1944–1995), actress
 - Helen Thomas (1966–1989), peace activist
 - Imogen Thomas (born 1982), model
 - Louie Myfanwy Thomas (1908–1968), novelist
 - Lucy Thomas (1781–1847), businesswoman
 - Lynda Thomas (born 1981), musician, singer-songwriter
 - Madoline Thomas (1890–1989), actress
 - Margaret Thomas (1779–?), hymnwriter
 - Queenie Thomas (1898–1977), film actress
 - Rachel Thomas (1905–1995), actress
 - Sarah Thomas (born 1981), field hockey player
 - Sian Thomas (born 1953), actress
 - Hester Thrale (1741–1821), diarist
 - Lily Tobias (1887–1984), novelist, short story writer, activist
 - Angela Tooby (born 1960), athlete, runner
 - Susan Tooby (born 1960), athlete, runner
 - Catherine Tregenna (active since 2000s), playwright, scriptwriter, actress
 - Barbara Margaret Trimble (1921–1995), novelist
 - Hayley Tullett (born 1975), athlete, runner
 - Bonnie Tyler (born 1951), singer
 - Irene Steer (1889–1947), swimmer
 
U
- Meena Upadhyaya (active since 2000s), medical geneticist
 
V
- Hilda Vaughan (1892–1985), novelist, short story writer, playwright, author of The Invader
 - Leona Vaughan (born 1995), actress
 - Lisa Victoria (born 1973), actress
 
W
- Kirsty Wade (born 1962), athlete, runner
 - Helen Wadsworth (born 1964), golfer
 - Lucy Walter (c.1630–1658), mistress of Charles I
 - Melanie Walters (born 1963), actress
 - Jo Walton (born 1964), Welsh-Canadian romance and science fiction novelist, author of Tooth and Claw
 - Anna Laetitia Waring (1823–1910), poet, hymnist
 - Myfanwy Waring (born 1974), actress
 - Mary Wynne Warner (1932–1998), mathematician
 - Elizabeth Andrew Warren (1786–1864), botanist and marine algolologist
 - Sarah Waters (born 1966), novelist, author of Fingersmith
 - Elizabeth Watkin-Jones (1877–1966), children's author
 - Megan Watts Hughes (1842–1907), singer, songwriter, scientist
 - Alis Wen (born 1520), Welsh-language poet
 - Olive Wheeler (1886–1963), educationist, psychologist and university lecturer
 - Susie Wild (born 1979), novelist, journalist, editor, strong connections with Wales
 - Alis Wen (fl. 16th century), poet
 - Anna Williams (1706–1783), poet
 - Betty Williams, (born 1944), politician
 - Buddug Williams (active since the 1990s), actress
 - Grace Williams (1906–1977), composer
 - Jane Williams (1806–1885), biographer, non-fiction works, many about Wales
 - Margaret Lindsay Williams (1888–1960), portrait painter
 - Maria Jane Williams (c.1794–1873), musician, folklorist
 - Annie Williams (born 1942), still life watercolour painter who grew up in Wales
 - Sian Williams (born 1990), rugby union player
 - Sue Williams (born 1956), visual artist
 - Saint Winifred (fl. 7th century), saint
 - Bethan Witcomb (active since 2010), actress
 - Katy Wix (born 1980), actress, comedian
 - Leanne Wood (born 1971), politician
 - Mary Myfanwy Wood (1882–1967), missionary
 - Frances Elizabeth Wynne (1835–1907), painter, sketcher
 - Sarah Edith Wynne (1849–1897), soprano
 
Y
- Paula Yates (1959–2000), television presenter, non-fiction writer
 - Megan York (born 1987), rugby union player
 
Z
- Catherine Zeta-Jones (born 1969), actress
 
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