LSI may refer to:
Science and technology
- Large-scale integration, integrated circuits with tens of thousands of transistors
 - Latent semantic indexing, a technique in natural language processing
 - LSI-11, an early large-scale integration computer processor that implemented the DEC PDP-11 instruction set
 - Langelier saturation index, a measure for water's tendency to form scale
 - Linear shift-invariant systems, the discrete equivalent of linear time-invariant systems
 
Organizations
- LSI Corporation, a technology company founded in 1981 as LSI Logic Corporation
 - Lynch Syndrome International, non-profit organisation supporting those affected by Lynch Syndrome
 - Labour and Socialist International, a multinational federation of left wing political parties and trade unions active between 1923 and 1940
 - Socialist Movement for Integration (Lëvizja Socialiste për Integrim), a political party in Albania
 - Lear Siegler Incorporated, a technology company active from 1961 to 2002
 - Lingkaran Survei Indonesia, a survey company in Indonesia
 
Transportation
- Lake Superior and Ishpeming Railroad, a railroad service in Michigan, United States
 - Sumburgh Airport (IATA airport code) in Shetland, Scotland
 
Music
- "LSI (Love Sex Intelligence)", a single by The Shamen
 - Long-string instrument, a musical instrument
 
Other uses
- Landing ship, infantry, a type of troopship or post World War II a landing craft
 - La Salle Institute, a college preparatory school
 - Linguistic Survey of India, a survey of the languages of British India directed by G.A. Grierson
 - Logical Sensory Introvert, a socionics type
 - Lighting & Sound International, a trade magazine
 
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