Knighton may mean:
Places in England
- Knighton, Devon, a location
 - Knighton, Isle of Wight
 - Knighton, Leicester, Leicestershire, a suburb
 - Knighton, Newcastle-under-Lyme, Staffordshire
 - Knighton, Oxfordshire
 - Knighton, Poole, a location
 - Knighton, Somerset, a location
 - Knighton, Stafford, Staffordshire
 - Knighton, West Dorset, a location
 - Knighton, Wiltshire
 - Knighton, Worcestershire, hamlet in Inkberrow parish
 - Knighton on Teme, Worcestershire, village and parish
 
Places in Wales
- Knighton, Powys a market town on the English/Welsh border 
- Knighton railway station serving the town
 - Knighton Town F.C., its football club
 
 
People
- Henry Knighton (d. 1396), English churchman and chronicler
 - Arthur Henry Knighton-Hammond (1875–1970), English artist
 - Brad Knighton (born 1985), American professional soccer player
 - Brian Knighton (1971–2016), American professional wrestler better known as Axl Rotten
 - Conor Knighton (born 1981), American actor, host, and television producer
 - Dorothea Knighton (1780–1862), English artist
 - Erriyon Knighton (born 2004), American sprinter
 - Ken Knighton, English former footballer, coach and manager
 - Michael Knighton, English businessman
 - Richard Knighton (born 1969), senior Royal Air Force officer and engineer
 - Robert Wesley Knighton (1941–2003), American serial killer
 - Terrance O'Knighton (born 1986), American football coach and former defensive tackle
 - William Knighton (1776 – 1836), English nobleman, Private Secretary to the Sovereign under George IV
 - William C. Knighton (1864–1938), American architect
 - William Myles Knighton (born 1931), British civil servant
 - Zachary Knighton, American actor
 
Other uses
- West Knighton (disambiguation), multiple uses
 - Knighton Woods, part of Epping Forest near Buckhurst Hill in Essex, England
 
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