John Keenan may refer to:
- John F. Keenan (born 1929), United States federal judge in New York
 - John Keenan (bishop) (born 1964), Bishop of Paisley, Scotland
 - John Keenan (Gaelic footballer) (born 1942), Irish retired sportsperson
 - John Keenan (Medal of Honor) (c. 1840–1906), United States Army soldier during the Indian Wars
 - John D. Keenan (born 1965), member of the Massachusetts House of Representatives
 - John F. Keenan (state senator) (born 1964), member of the Massachusetts Senate
 - John R. Keennan (1939–2015), baseball scout for the Los Angeles Dodgers club
 
Others
- John Keenan (Holby Blue), fictional character in the British television series Holby Blue
 
See also
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