Hugo López may refer to:
- Hugo López-Gatell Ramírez (born 1969), Mexican epidemiologist
- Hugo López (athlete) (born 1973), Guatemalan racewalker
- Hugo López (basketball) (born 1975), Spanish basketball player and coach
- Hugo Lopez (Canadian football) (born 1987), Nicaraguan CFL player
- Hugo López (footballer) (born 1988), Spanish footballer
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