Desmoulins, de Moulins, des Moulins or Demoulin may refer to:
- Georges Demoulin (1919–1994), Belgian entomologist
- Michel Demoulin (born 1965), Belgian athlete
- Nicolas Démoulin (born 1972), French politician
- Robert Demoulin (1911–2008), Belgian academic
- Jacques Démoulin (1905-1991), French painter
- Jean de Moulins (d. 1353), French cardinal
- Roger de Moulins (d. 1187), Grand Master of the Knights Hospitaller
- André Desmoulins (fl. 1940), French cyclist
- Camille Desmoulins (1760–1794), French revolutionary leader
- Lucile Desmoulins née Duplessis (1770–1794), wife of Camille
- Charles Des Moulins (1798–1875), French naturalist
- Guyart des Moulins (1251–1322), French monk
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