Charles Cline may refer to:
- Charles E. Cline (1858–1914), American politician in the state of Washington
 - Charlie Cline (1931–2004), musician
 - Doug Cline (Charles Douglas Cline, 1938–1995), American football player
 
See also
- Charles H. Kline (1870–1933), mayor of Pittsburgh
 - Charles Klein (disambiguation)
 
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